Disclaimer: The information provided on this site is for informational purposes only and is not intended as a substitute for professional medical advice. Always consult a healthcare professional before starting any new supplement or health regimen. These statements have not been evaluated by the FDA, and these products are not intended to diagnose, treat, cure, or prevent any disease.
Supplements:
- Qualia NAD+ (Dave Asprey endorsed)
- BioStack Labs NAD Regen (Ben Greenfield endorsed)
- Rho Nutrition Liposomal NAD+ (Gary Brecka endorsed)
What is NAD+:
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells that plays a crucial role in energy metabolism and cellular health. Supplementing with NAD+ (or its precursors like NR (nicotinamide riboside) or NMN (nicotinamide mononucleotide)) is believed to provide several potential benefits:
1. Energy Production (ATP Synthesis)
NAD+ is essential for mitochondrial function, as it helps convert food into ATP (the body’s main energy source). Lower NAD+ levels are associated with fatigue and decreased cellular energy.
2. Cellular Repair & Longevity
NAD+ activates sirtuins, a group of proteins linked to DNA repair, inflammation reduction, and lifespan extension. Some research suggests that higher NAD+ levels may slow aging and improve cellular resilience.
3. Brain Function & Cognitive Health
NAD+ is involved in neuroprotection and has been studied for its role in Alzheimer’s, Parkinson’s, and cognitive decline. Some users report improvements in mental clarity and focus.
4. Metabolic Health
Higher NAD+ levels are linked to better insulin sensitivity, improved metabolism, and weight management, making it of interest for those concerned with diabetes and metabolic syndrome.
5. Muscle & Exercise Recovery
NAD+ supports muscle endurance, mitochondrial efficiency, and recovery. Some athletes take NAD+ precursors to enhance performance and reduce post-exercise fatigue.
6. Inflammation & Immune Function
NAD+ influences inflammatory pathways and may help reduce chronic inflammation, a key driver of aging-related diseases.
Does It Work?
Animal studies show promising effects on aging, metabolism, and brain health.
Human studies are still emerging, with mixed but generally positive findings on energy, cognitive function, and metabolic markers.
NAD+ itself has poor bioavailability when taken orally, so most supplements use precursors like NMN or NR.
MGD’s 